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All Journal Jurnal Ilmu-Ilmu Perairan dan Perikanan Indonesia Jurnal Ilmu Dasar JURNAL PIJAR Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Pijar MIPA
Dwi Soelistya Dyah Jekti
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Earth & Planetary Sciences Education Materials Science & Nanotechnology Mathematics Physics

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Journal : Jurnal Ilmu Dasar

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Nyale Sea Worm As Antibacterial Substances Dwi Soelistya Dyah Jekti; Agus Abhi Purwoko; Zainul Muttaqin
Jurnal ILMU DASAR Vol 9 No 2 (2008)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

Nyale is a sea worm that belongs to class of polychaete. It appears on a huge crowd, usually five days after the monsoon in February, at the surface of the sea for breeding. The colors of the female and male worms are green and brown, respectively. The worms are collected in nyale season, freezed-dryer, and extracted with ethyl acetate. Antimicrobial activity properties of the male worm extract are carried out toward benthos bacteria and clinical isolate bacteria using ciprofloxacin as comparing agent. The results show that, after colom chromatography, fraction number 1 and 4 have the best antibacterial activities (broadest spectrum) toward clinical isolate bacteria. All eleven fractions show also antibacterial activities toward nine benthos bacteria. The minimum inhibitory concentration (MIC) of fractions 1 and 4 toward six clinical isolate bacteria is 100 μg/ml. Meanwhile, fraction 4 exhibits two peaks in its HPLC chromatrogram.
Co-Authors A. Wahab Jufri A.A. Ketut Agung Cahyawan W Agus Abhi Purwoko Agus Ramdani Dewa Ayu Citra Rasmi Eny Yulianti Guplin - Hari Suryawati I Gst Ayu Suartini Gayatri Jamaluddin - Jamaluddin Jamaluddin Lalu Zulkifli Mochamad Maswan Raden Sumiadi Raden Sumiadi, Raden Raskun . Sahratullah Sahratullah Sumarjan . Titi Hariyati W Kastoro Yayuk Andayani Zainul Muttaqin